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Uptake of CAR T-cell therapy has been slow, largely limited to large transplant centers where clinical trials were performed. 11,12 Many more CAR T-cell therapies are in development, with more than 600 clinical trials underway globally. The field continues to rapidly evolve, with the manufacturers of brexucabtagene autoleucel and a second BCMA-targeted CAR T-cell therapy, ciltacabtagene autoleucel, seeking approval of their products for the treatment of relapsed or refractory ALL with a Prescription Drug User Fee Act (PDUFA) date of Octoand multiple myeloma with a PDUFA date of November 29, 2021, respectively. 3 Table 1 5-10 summarizes the currently approved CAR T-cell products. 3,4 All of the aforementioned CAR T-cell products target the CD19 antigen, but in March 2021, idecabtagene vicleucel made history as the first B-cell maturation antigen (BCMA)-targeting CAR T-cell therapy approved for the treatment of adult patients with relapsed/refractory multiple myeloma. In July 2020, brexucabtagene autoleucel became the first approved product for relapsed or refractory mantle cell lymphoma (MCL), while lisocabtagene maraleucel was approved for the treatment of LBCL in February 2021. In the past 2 years, these CAR T-cell products have been joined by 3 others. 1,2 Axicabtagene ciloleucel is now also approved for the treatment of patients with relapsed or refractory follicular lymphoma.

In 2018, just 2 CAR T-cell therapies were commercially available: axicabtagene ciloleucel for the treatment of relapsed/refractory large B-cell lymphoma (LBCL), and tisagenlecleucel for the treatment of pediatric and young adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL) and adult patients with relapsed or refractory LBCL. Their use is rapidly expanding as more become approved by the FDA. In the meantime, payers and providers are tasked with facing the logistical complexities of CAR T-cell therapy and developing new payment and reimbursement strategies to ensure value-based care and optimal access today.Д¬himeric antigen receptor (CAR) T-cell therapies represent a paradigm shift for the treatment of several previously incurable refractory hematologic malignancies. CAR T-cell therapies currently have the potential to be cost-effective however, improved safety and efficacy, outpatient administration, and a streamlined manufacturing process could make them even more so. While uptake of CAR T-cell therapy is rapidly ramping up, there remain significant barriers to effective implementation and patient access, not least their price tag and substantial ancillary costs of care. Five CAR T-cell products are now approved by the US Food and Drug Administration for a growing number of cancer indications and a global market worth billions is anticipated in the next 5 years. For more information, please contact Enrollment Services.Since the historic approval of tisagenlecleucel for the treatment of B-cell acute lymphoblastic leukemia in 2017, chimeric antigen receptor (CAR) T-cell therapies have altered the treatment paradigm for hematologic malignancies. Please note that ECSI monthly payment plans cannot be used towards Study Away payments. Payment for the remaining balance may be made by electronic check via the students MyFurman account. Any applicable financial aid will be applied to this bill. The final payment for the study away program will be billed by Furman in accordance with the standard semester billing procedures. Program deposits and interim payments will be credited to your student account for the designated study away term and appear as a credit on the final billing for that term.

On the checkout screen, select your method of payment, complete the required fields and click on the button that says 'Process Payment'.

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Enter the Student Information, Select the Term you are studying away on, Click on the green button that says 'Add' and Click on the button that says 'Continue' (students who are studying away for a full academic year should select the Fall Term).Click on the purple button that reads 'Make a One-Time Payment'.Under 'Make a One-Time Payment' select Furman University-Study Away Deposits from the drop down.Do not log into your Furman billing account.Study Away Program deposits should be paid online through Furman's payment website. Program Expectations: Physical & Mental Health.Diversity, Identity & Study Away Resources.Receiving Academic Credit & Transfer Credit.Furman Exchange Program: Incoming Exchange Student.

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